Depletion of B lymphocytes is associated with suppression of inflammatory activity in multiple sclerosis. The aim of a study was to assess the safety and efficacy of Atacicept, a recombinant fusion pr ...

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Chronic inflammatory demyelinating polyradiculoneuropathy is a rare acquired immune-mediated progressive or relapsing disorder causing peripheral neuropathic disease of duration more than two months. ...

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In patients with relapsing–remitting multiple sclerosis ( RRMS ), a scoring system based on new magnetic resonance imaging ( MRI ) active lesions, relapses and sustained disability progression after a ...

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Acute transverse myelitis ( ATM ) in children is a rare and often severe disease for which there are few known prognostic factors, particularly the subsequent risk of multiple sclerosis diagnosis. ...

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A study has assessed the sensitivity of optic coherence tomography ( OCT ) and visual evoked potentials ( VEPs ) to visual pathway abnormalities in multiple sclerosis. A total of 40 subjects with m ...

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Azathioprine ( Imuran ) is a common immunosuppressive drug used for relapse prevention in neuromyelitis optica ( NMO ). The objective of this study was to assess efficacy, tolerability and retentio ...

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High blood pressure is a prognostic factor for acute stroke, but blood pressure variability might also independently predict outcome. Researchers have assessed the prognostic value of blood pressure ...

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Alemtuzumab ( Lemtrada ), an anti-CD52 monoclonal antibody, has increased the risk of thyroid dysfunction in CAMMS223, a phase 2 trial in relapsing-remitting multiple sclerosis. The objective of th ...

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The FDA ( Food and Drug Administration ) has allowed marketing of the first device as a preventative treatment for migraine headaches. This is also the first transcutaneous electrical nerve stimulatio ...

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Researchers have reported the findings from a clinical trial in which a group of patients clinically diagnosed with probable Alzheimer’s disease ( AD ) were discriminated from an age-matched group of ...

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It is often assumed that blood pressure increases acutely after major stroke, resulting in so-called post-stroke hypertension. In view of evidence that the risks and benefits of blood pressure-lowerin ...

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The aim of a study was to analyze morphological and functional aspects of cerebral veins by means of ecocolor- Doppler in young ( i.e., less than or equal to 30 years old ) and older ( i.e., greater t ...

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Peroxisome proliferator-activated receptor gamma ( PPAR-gamma ) agonists are insulin-sensitising drugs used for the treatment of insulin resistance. In addition to lowing glucose in diabetes, these dr ...

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Glioblastoma ( GBM ) is the most common primary malignant adult brain tumor and, despite treatment advances in recent years, the average survival of patients enrolled in clinical trials is less than 1 ...

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The antidepressant drug Citalopram ( Celexa, Cipramil, Seropram ), significantly relieved agitation in a group of patients with Alzheimer's disease. In lower doses than those tested, the drug might be ...

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Giving intravenous Magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, a ...

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Individuals with two or more first-degree relatives who have had aneurysmal subarachnoid haemorrhage ( aSAH ) have an increased risk of aneurysms and aSAH. Researchers investigated the yield of long ...

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Chronic cerebrospinal venous insufficiency ( CCSVI ) was initially defined as a clinical syndrome comprising stenoses of the internal jugular and/or azygos veins, characterized by collateral venous ou ...

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Alzheimer's disease is characterized by amyloid-beta plaques, neurofibrillary tangles, gliosis, and neuronal loss. Solanezumab, a humanized monoclonal antibody, preferentially binds soluble forms of a ...

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Guillain-Barré syndrome ( GBS ) is an acute polyneuropathy with a variable degree of weakness that reaches its maximal severity within 4 weeks. The disease is mostly preceded by an infection and gener ...

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