Early results of the SAMMPRIS ( Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis ) trial has showed that, by 30 days, 33 ( 14.7% ) of 224 patients in ...

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Dopamine agonists are often used as first-line monotherapy for the symptomatic control of Parkinson's disease. However, dopamine agonist monotherapy typically becomes inadequate within a few years, at ...

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A study ( Study 307 ) has evaluated safety, tolerability, seizure frequency, and regional variations in treatment responses with the AMPA antagonist, Perampanel ( Fycompa ), in a large extension study ...

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Preliminary efficacy and safety data on 27 children and young adults with treatment-resistant epilepsy who have been treated with an investigational Cannabidiol ( CBD ) product candidate, Epidiolex, f ...

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The FDA ( Food and Drug Administration ) has allowed marketing of the first motorized device intended to act as an exoskeleton for people with lower body paralysis ( paraplegia ) due to a spinal cord ...

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Intraluminal defects such as membranes, immobile leaflets of the valves and septa have been described in the internal jugular vein ( IJV ) and classified by a quite recent Consensus among the truncul ...

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The aim of a phase III, placebo-controlled trial, including an open-label extension, was to investigate the safety / tolerability and efficacy of long-term adjunctive Zonisamide ( Zonegran ) and its i ...

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A study has evaluated the effect of Vitamin D analogue, Alfacalcidol, on multiple sclerosis-related fatigue. Fatigue is one of the most common and disabling symptoms of multiple sclerosis, not effi ...

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The uncertainties of the actual etiological basis of multiple sclerosis make it difficult to reach a conclusive statement about the optimal therapeutic management of the disease, which may differ depe ...

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Deep brain stimulation ( DBS ) is the surgical procedure of choice for patients with advanced Parkinson disease. The globus pallidus internus ( GPi ) and the subthalamic nucleus ( STN ) are commonly t ...

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An enzyme closely associated with genetic forms of Parkinson’s disease appears to play a larger role in its progression than previously thought, according to researchers at the University of Alabama a ...

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The best surgical tactics in Chiari malformation are not established yet. A group of patients which firstly were treated conservatively and after some period were operated on, was followed up. The ...

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The aim of the study was to determine the type and frequency of peripheral neuropathy in patients with inflammatory disorders taking anti-TNF alpha agents. Researchers at Lausanne University Hospit ...

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The aim of a study was to evaluate the existence of pathologic retinal deposits in patients with possible Alzheimer’s disease. Researchers have examined 20 patients with mild cognitive impairment, ...

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Idiopathic Pisa syndrome in Parkinson’s disease is a rare entity with only sporadic single case descriptions. Therefore, its pathophysiology has been poorly investigated. Researchers have performed ...

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Sleeve gastrectomy is a safe and effective fast growing weight loss surgery option. Nevertheless complications are not rare. Five patients who developed sensorimotor symptoms after sleeve gastrecto ...

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Epidemiological data have indicated that migraine is an independent stroke risk factor. Recent data suggest that migraine mutations increase brain vulnerability to ischemia via excitatory mechanisms. ...

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Stereotactic lesions have been occasionally performed in Huntington’s chorea since the dawn of functional stereotactic surgery, however, with modest results. Despite the success of deep brain stimul ...

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Dopamine agonists are used as initial symptomatic therapy for early Parkinson’s disease, escalating dose or addition of Levodopa needed over time to maintain symptom control. Increasing dopamine ago ...

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NARCOMS has provided a registry of 37,000+ patients with multiple sclerosi. Disability, measured by Patient Determined Disease Steps ( PDDS ), was retrospectively compared between NARCOMS participants ...

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